Intermediate Filament Types

INTERMEDIATE FILAMENTS BY SEQUENCE HOMOLOGY GROUPS
Intermediate filaments can be identified as belonging to one of six sequence homology groups, i.e. type I to type VI, based on their DNA and amino acid sequences. Their properties and characteristics are briefly outlined below.

TYPE I & II (keratins)

TYPE III (desmin, glial fibrillary acidic protein, peripherin and vimentin)

TYPE IV (α-internexin, NF-H, NF-L, NF-M, nestin, syncoilin, synemin α and synemin β)

TYPE V (lamins)

TYPE VI (eye lens intermediate filaments)

 

Last modified: June 29 2007 17:06:06.

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