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There are four type III genes in this group: desmin intermediate filaments of muscle cells (all types); vimentin intermediate filaments in fibroblasts, lymphocytes, endothelial cells and many mesenchymal tissues; peripherin, mostly in peripheral neurons, that can coassemble with type IV proteins, and GFAP (glial fibrillary acidic protein) is found in astrocytes and glial cells. Although members of this group can make homopolymeric filaments in vitro, they may assemble as heteropolymers in tissues.
Click here for statistics of type III intermediate filament proteins. Last modified: August 27 2008 16:55:24. |